Mayfair is a strong base for business travel because it puts you close to central London, major hotels, private clubs, offices, and transport links. If you want a practical stay with easy access to meetings, the best areas are usually near Berkeley Square, Grosvenor Square, Bond Street, and Park Lane.
For business trips, the most useful options are usually full-service hotels with reliable Wi-Fi, meeting space, concierge support, and easy transport access. The Biltmore Mayfair, Flemings Mayfair, The Mayfair Townhouse, and other business-focused hotels in the area all position themselves for corporate stays and central convenience.
If your work schedule is heavy, stay near Bond Street or Green Park so you can move around the West End quickly. If you want a quieter base with easy access to meetings and dining, Grosvenor Square and the streets around Berkeley Square are often better choices.
For longer stays, a serviced apartment can make more sense than a hotel. It gives you more space, a kitchen, and a quieter setup for working, which is useful if you are in London for more than a few nights.